1988 - 1991 Postdoctoral Fellow, Kennedy Krieger Institute for Handicapped Children, Johns Hopkins School of Medicine Baltimore, U.S.A.
1989 Summer School Student in Molecular Biology, Jackson Laboratory Bar Harbor and Johns Hopkins University Baltimore, U.S.A.
1990 - 1991 Postdoctoral Fellow, Howard Hughes Medical Institute, Johns Hopkins School of Medicine Baltimore, U.S.A.
1991 - 1993 Instructor and Faculty Member, Department of Pediatrics, Johns Hopkins School of Medicine Baltimore, U.S.A.
1993 - 1995 Research Fellow, Department of Pediatrics, University of Düsseldorf
1995 - 2000 Ass. Professor, Dept. of Pediatrics, University of Düsseldorf
2000 - 2002 University Professor, Department of Pediatrics and Pediatric Neurology, University of Düsseldorf
since 2002 University Professor and Chair, Department of Pediatrics and Pediatric Neurology, University of Göttingen
Molecular basis of peroxisome biogenesis: peroxisomal membrane proteins and their role in peroxisome assembly and function
Peroxisomal disorders: Clinical and molecular characterization of patients with peroxisome biogenesis
disorders and X-linked adrenoleukodystrophy
Leukodystrophies: Clinical, neuroradiological and molecular characterization of patients with unclassified leukodystrophies
Department of Pediatrics and Pediatric Neurology
University of Göttingen
phone: +49-551-39 8035
fax: +49-551-39 6252
Department Research Group
Roerig P, Mayerhofer P, Holzinger A, Gärtner J (2001): Characterization and functional analysis of the nucleotide binding fold in human peroxisomal ATP-binding cassette transporters. FEBS Lett 24674:1-7.
Brosius U, Dehmel, T, Gärtner J (2002): Two different targeting signals direct human PMP22 to peroxisomes. J Biol Chem 277:774-784.
Steinfeld R, Steinke HB, Isbrandt D, Kohlschütter A, Gärtner J (2004): Mutations in classical late infantile neuronal ceroid lipofuscinosis disrupt transport of tripeptidyl-peptidase I to lysosomes. Hum Mol Genet 13:2483-2491.
Uhlenberg B, Schuelke M, Ruschendorf F, Ruf N, Kaindl AM, Henneke M, Thiele H, Stoltenburg-Didinger G, Aksu F, Topaloglu H, Nürnberg P, Hübner C, Weschke B, Gärtner J (2004): Mutations in the gene encoding gap junction protein alpha 12 (connexin 46.6) cause Pelizaeus-Merzbacher-like disease. Am J Hum Genet 75:251-260.
Steinfeld R, Reinhardt K, Schreiber K, Hillebrand M, Kraetzer R, Brück W, Saftig P, Gärtner J (2006): Cathepsin D deficiency is associated with a human neurodegenerative disorder. Am J Hum Genet 78: 988-989.